2013년 대한면역학회 추계학술대회, 2013, 02, 139─139

Protective activity of monoclonal antibody against the poly-γ-D-glutamic acid capsule of Bacillus anthracis in enhanced lethal toxin activity due to capsule and anthrax spore challenge

Jeyoun Jang, Minhui Cho, Hae-Ri Lee, Kiweon Cha, Jeong-Hoon Chun, Kee-Jong Hong, Jungchan Park, Gi-eun Rhie

Abstract

Background: The poly-γ-D-glutamic acid (PGA) capsule, a major virulence factor of Bacillus anthracis, protects bacilli from immune surveillance and allows its unimpeded growth in the host. Recently, the importance of the PGA in the pathogenesis of anthrax infection has been reported. The PGA capsule is associated with lethal toxin (LT) in the blood of experimentally

• ISBN or ISSN: 0000-0000

• 본 연구는 질병관리본부 연구개발과제(과제번호 2011-N45001-00) 연구비를 지원받아 수행되었습니다.
• This research was supported by a fund(code 2011-N45001-00) by Research of Korea Centers for Disease Control and Prevention.