Diagn Microbiol Infs Dis, 2014, 01, 148─150

Structure and transfer of the vanA cluster in vanA-positive,vancomycin-susceptible Enterococcus faecium, and its revertant mutant

Young-Hee Jung, Y Lee, S Lee, J Yoo, J Yoo, H Kim, O Kim, J Yu

Abstract

Of 18 vanA-positive vancomycin-susceptible Enterococcus faecium isolates, vanRS in the vanA cluster was detected in all isolates, while vanHAX was detected in only 2 isolates. Following exposure to glycopeptides, 22.2% of vancomycin-susceptible E. faecium (VSE) converted into vancomycin-resistant E. faecium. The vanA cluster of the revertant mutant was transferred to the VSE isolates.

• ISBN or ISSN: 0732-8893

• 본 연구는 질병관리본부 연구개발과제(과제번호 2009-N44001-00) 연구비를 지원받아 수행되었습니다.
• This research was supported by a fund(code 2009-N44001-00) by Research of Korea Centers for Disease Control and Prevention.