Journal of Nutrition and Health, 2014, 02, 176─185

한국 다낭성난소증후군 환자에서 대사증후군과 식이 플라보노이드 섭취와의 관련성 (Relationship between dietary flavonoids intake and metabolic syndrome in Korean women with polycystic ovary syndrome)

오지수, 안미진, 한찬정, 김혜숙, 권오란, 정혜원, 장남수 (Ahn, Mi Jin, Han, Chan Jung, Kim, Hyesook, Kwon, Oran, Chung, Hye Won, Chang, Namsoo)

Abstract

Purpose: The purpose of this study was to investigate the relationship between dietary flavonoids intake and metabolic syndrome (MetS) in Korean women with polycystic ovary syndrome (PCOS). Methods: A total of 223 subjects (mean age; 27.3 ± 4.2 yrs, range; 17-38 yrs) were divided into the MetS group (n = 27) and non-MetS group (n = 196). Dietary intake data were assessed by 24-hour recall method for two non-consecutive days and the average of the two days was used to estimate the usual dietary intake. Dietary habits were assessed using the Mini Dietary Assessment (MDA) score. We analyzed the intakes of six flavonoid classes (anthocyanidins, flavan-3-ols, flavanones, flavones, flavonols, and iso-flavones) using a flavonoids database. Results: After adjustment for age, total energy intake, alcohol consumption, smok-ing, regular exercise, and oral contraceptive use, dietary flavonols intake was significantly lower in the MetS group (5.1 ± 2.4 mg/d) than in the non-MetS group (8.9 ± 2.8 mg/d) (p = 0.0472). Intakes of other flavonoids except for flavonols did not differ between the two groups. In MDA scores, significant differences were observed only for that related to daily con-sumption of fruit or fruit juice (p = 0.0180). A significant inverse relationship was observed between flavonols intake and the risk of MetS (4th vs. 1st quartile, OR = 0.11, 95% CI = 0.02-0.62, p for trend = 0.0131). Conclusion: These results sug-gest that higher intake of flavonols may be beneficial for MetS in PCOS women.

• ISBN or ISSN: 2288-3886

• 본 연구는 질병관리본부 연구개발과제(과제번호 2010-만성(용)-7) 연구비를 지원받아 수행되었습니다.
• This research was supported by a fund(code 2010-Non-communicable diseases-7) by Research of Korea Centers for Disease Control and Prevention.